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Description
Palmitoylethanolamide (PEA) is a supplement recognized for its anti-inflammatory and analgesic properties, often used to support pain relief and neurological health. Naturally occurring in the body, PEA plays a role in regulating the immune response and reducing chronic inflammation. This supplement is beneficial for conditions associated with nerve pain, such as neuropathy, and it may enhance overall nerve function and comfort. PEA works synergistically with other natural anti-inflammatories like quercetin and curcumin, offering a comprehensive approach to pain management. Due to its calming effects, PEA is suitable for those seeking natural support for pain and inflammation without sedative side effects.
When To Take It
PEA can be taken any time of day, with or without food, though for consistent relief, dividing the dose between morning and evening may optimize its effects.
Synergy and Antagonism
PEA works well with quercetin, curcumin, and omega-3 fatty acids to enhance pain relief and inflammation control. However, high doses may interfere with immunomodulatory compounds like CBD and adaptogenic herbs, such as ashwagandha extract, rhodiola extract, and holy basil extract, potentially reducing their effects on immune regulation.
PEA works well with quercetin, curcumin, and omega-3 fatty acids to enhance pain relief and inflammation control. However, high doses may interfere with immunomodulatory compounds like CBD and adaptogenic herbs, such as ashwagandha extract, rhodiola extract, and holy basil extract, potentially reducing their effects on immune regulation.
Palmitoylethanolamide
May Help With The Following Conditions
At present, there is no established association between this supplement and any medical condition listed on the Health Status pages.
Category
Fatty Acids
Warnings
Individuals on immunosuppressive therapy should consult a healthcare provider before using PEA. Pregnant or breastfeeding women should also seek guidance from a healthcare professional before use.