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Description
"Methylsulfonylmethane" (MSM) is a supplement containing a naturally occurring sulfur compound found in plants and animal tissues. It plays a role in collagen synthesis, contributing to connective tissue strength and overall structural integrity. Its involvement in inflammatory regulation and post-exercise recovery supports musculoskeletal function and mobility. MSM is included in various formulations designed for joint care and tissue maintenance. Its bioavailable sulfur content makes it a valued component in structural and recovery-focused applications.
Category
Additional Nutrients
When To Take It
MSM can be taken at any time, though it is often consumed with food to reduce the likelihood of gastrointestinal discomfort. Some individuals prefer to take it in the morning to support joint health throughout the day.
Synergy and Antagonism
MSM works synergistically with glucosamine and chondroitin to support joint health and reduce inflammation. It also pairs well with vitamin C to promote collagen synthesis and improve skin and joint health. There are no well-documented antagonistic interactions for MSM.
MSM works synergistically with glucosamine and chondroitin to support joint health and reduce inflammation. It also pairs well with vitamin C to promote collagen synthesis and improve skin and joint health. There are no well-documented antagonistic interactions for MSM.

Methylsulfonylmethane
May Help With The Following Conditions
At present, there is no established association between this supplement and any medical condition listed on the Health Status pages.
Warnings
Caution is advised when using MSM during pregnancy or breastfeeding. High doses of MSM may cause gastrointestinal discomfort, such as bloating, nausea, or diarrhea. Consult a healthcare provider before use if taking blood-thinning medications or if you have known sensitivities.