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Description
Benfotiamine is a highly bioavailable, fat-soluble derivative of Vitamin B1 (thiamine), known for its superior absorption and longer-lasting effects. This compound is widely recognized for supporting nerve health, particularly in individuals with diabetic neuropathy and alcoholic neuropathy, by helping to protect nerves from glucose-related damage. By activating the enzyme transketolase, benfotiamine prevents the harmful effects of oxidative stress and advanced glycation end-products (AGEs). Beyond nerve protection, benfotiamine also supports vascular health by improving blood flow and reducing the risk of complications from high blood sugar. Regular supplementation with benfotiamine may improve nerve function, support blood glucose regulation, and promote overall metabolic health.
When To Take It
Benfotiamine is most effective when taken with meals, especially those containing fat, due to its fat-soluble nature. This helps maximize absorption and supports its benefits on metabolism and nerve health.
Synergy and Antagonism
Benfotiamine works in synergy with thiamine (vitamin B1) and alpha-lipoic acid to enhance carbohydrate metabolism and support nerve health. No well-documented antagonistic interactions exist for benfotiamine.
Benfotiamine works in synergy with thiamine (vitamin B1) and alpha-lipoic acid to enhance carbohydrate metabolism and support nerve health. No well-documented antagonistic interactions exist for benfotiamine.
Benfotiamine
May Help With The Following Conditions
At present, there is no established association between this supplement and any medical condition listed on the Health Status pages.
Category
Vitamins
Warnings
Although benfotiamine is considered generally safe, individuals with pre-existing medical conditions, such as diabetes, should consult with a healthcare provider before using it. Its effect on pregnancy and breastfeeding has not been sufficiently studied, so caution is advised in these cases.