Description
Vitamin B6, also known as pyridoxine, is a crucial water-soluble vitamin that needs to be replenished regularly, as it is excreted within eight hours of consumption. Pyridoxine is vital for the absorption of vitamin B12 and works synergistically with other B vitamins like B1 and B2 to support overall metabolism. It aids digestion by promoting the production of hydrochloric acid, which improves the absorption of proteins and fats. Vitamin B6 also helps lower homocysteine levels in the blood when combined with folic acid, which may reduce the risk of heart disease. It is essential for brain and nervous system health, preventing issues like muscle cramps and nerve pain. Furthermore, it supports the production of nucleic acids like DNA and RNA, crucial for cell growth and repair, and enhances immune system function. Regular intake of vitamin B6 can aid in skin health and fluid balance due to its mild diuretic properties.
Functions in the Body
Category
Deficiency Symptoms
A vitamin B6 deficiency can lead to symptoms such as peripheral neuropathy, anemia, seizures, depression, a swollen tongue, weakened immune system, cracks at the corners of the mouth, and confusion.
Synergy & Antagonism
Vitamin B6 works synergistically with vitamin A, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B9, PABA, vitamin B12, vitamin C, vitamin E, chromium, copper, iron, potassium, magnesium, manganese, sodium, phosphorus, selenium, and zinc to support energy metabolism, brain function, and immune health. Excess calcium, copper, or iron can antagonize vitamin B6, reducing its effectiveness.
Vitamin B6
Warnings
Vitamin B6 should not be used in levodopa (L-dopa) treatment for Parkinson's disease, as it can reduce the drug’s effectiveness. It also interacts with antibiotics, antidepressants, chemotherapy medications, phenytoin (anti-seizure medication), and erythropoietin (used for anemia). Long-term high doses of vitamin B6 can lead to nerve damage.
Food Sources
Rich sources of vitamin B6 include nutritional yeast, whole-grain products, poultry, fish, nuts, peas, and bananas.
Time Frame
Vitamin B6 can be taken anytime, but for best results, it is recommended to take it early in the morning to support daily energy metabolism.
Depleted By
Vitamin B6 can be depleted by factors such as alcohol, antacids, corticosteroids, anticonvulsants, sedatives, bisphosphonates, nicotine, immunosuppressants, hormone replacements, hyperuricemia medications, diuretics, antidiabetic drugs, anti-cancer medications, caffeine, bronchodilators, blood pressure medications, antipsychotics, antiparasitics, antibiotics, antifungals, and antidepressants.