Description
Selenium is a vital trace mineral that plays a crucial role in maintaining overall health and cellular function. It is found in plant and animal sources, with its concentration largely depending on soil selenium levels. Selenium acts as an essential component of glutathione peroxidase, a powerful antioxidant enzyme, and also exhibits antioxidant effects on its own. This trace element is integral to thyroid hormone production, aiding in the regulation of metabolism and energy levels. Selenium further protects cells from oxidative stress, which can contribute to chronic diseases such as heart disease and cognitive decline. By supporting immune function and reducing inflammation, selenium plays a role in preventing certain cancers and enhancing cardiovascular health. Ensuring adequate intake of selenium through food or supplements is key for maintaining thyroid health, immune support, and antioxidant protection for overall wellness.
Functions in the Body
Category
Deficiency Symptoms
Selenium deficiency can result in increased cancer risk, cardiovascular disease, Keshan disease, Kashin-Beck disease, premature aging, muscle weakness, and cataracts.
Synergy & Antagonism
Selenium works synergistically with vitamin B3, vitamin C, vitamin E, calcium, copper, iron, potassium, manganese, sodium, and zinc to support antioxidant defenses, thyroid function, and immune health. It is antagonistic to vitamin A and heavy metals such as aluminum, cadmium, mercury, and lead, which can reduce its effectiveness.
Selenium
Warnings
Selenium supplementation should be avoided in people with skin cancer. It can interact with medications such as statins, antacids, chemotherapy drugs, corticosteroids, and birth control pills. Excessive selenium intake can also cause symptoms like nausea, hair loss, and nerve damage.
Food Sources
Selenium is naturally found in milk, poultry, fish, seafood, organ meats, whole grain products, and especially Brazil nuts.
Time Frame
Selenium can be consumed at any time, as it does not require a specific time for optimal absorption.
Depleted By
Selenium levels can be depleted by alcohol, antacids, corticosteroids, anticonvulsants, nicotine, hormone replacement therapy, anti-cancer medications, bronchodilators, blood pressure medications, antipsychotics, antibiotics, and antidepressants.