Description
"Selenium" is a trace mineral naturally present in soil, water, and various foods, playing a vital role in human physiology. It contributes to antioxidant defense, thyroid hormone regulation, and immune system efficiency. Enzymatic reactions involved in cellular detoxification and inflammatory control also require adequate selenium levels. This mineral is essential for selenoproteins, which regulate metabolic activity and cellular protection. Found in nuts, seafood, and whole grains, selenium remains crucial for overall physiological function.
Functions in the Body
Category
Deficiency Symptoms
Selenium deficiency can result in increased cancer risk, cardiovascular disease, Keshan disease, Kashin-Beck disease, premature aging, muscle weakness, and cataracts.
Synergists & Antagonists
Selenium works synergistically with vitamin B3, vitamin C, and vitamin E to enhance antioxidant activity. It also supports thyroid function alongside calcium, iodine, and zinc. Additionally, it pairs with copper, iron, potassium, and manganese for immune defense. However, excessive vitamin A and heavy metals (aluminum, cadmium, mercury, lead) act as antagonists, reducing its effectiveness.
Selenium
Warnings
Selenium supplementation should be avoided in people with skin cancer. It can interact with medications such as statins, antacids, chemotherapy drugs, corticosteroids, and birth control pills. Excessive selenium intake can also cause symptoms like nausea, hair loss, and nerve damage.
Food Sources
Selenium is naturally found in milk, poultry, fish, seafood, organ meats, whole grain products, and especially Brazil nuts.
Time Frame
Selenium can be consumed at any time, as it does not require a specific time for optimal absorption.
Depleted By
Selenium levels can be depleted by alcohol, antacids, corticosteroids, anticonvulsants, nicotine, hormone replacement therapy, anti-cancer medications, bronchodilators, blood pressure medications, antipsychotics, antibiotics, and antidepressants.