Description
Functions in the Body
N-Acetyl-L-Cysteine (NAC) is a stable form of the amino acid L-cysteine, essential for producing glutathione, one of the body’s most powerful antioxidants. NAC plays a crucial role in cellular detoxification by supporting the liver's ability to neutralize harmful substances like tobacco smoke, alcohol, and environmental toxins. It enhances the body's antioxidant defense system, helping protect cells from oxidative damage. NAC is widely used to treat chronic respiratory conditions such as bronchitis and asthma by reducing inflammation in the airways. Additionally, NAC may improve mental health by alleviating symptoms of depression and bipolar disorder. Its ability to support liver health, boost immune function, and protect cells from damage makes NAC an essential supplement for maintaining overall well-being.
Deficiency Symptoms
Since NAC is not an essential nutrient, there are no deficiency symptoms associated with its absence.
Synergy & Antagonism
N-acetyl-L-cysteine (NAC) works synergistically with glutathione by replenishing its levels, thereby enhancing antioxidant defense in the body. No significant antagonistic interactions have been documented for NAC.
N-ACETYL-L-CYSTEINE
Warnings
If you have peptic ulcers or are taking medications that cause gastric lesions, avoid using NAC. Caution should be applied during breastfeeding. NAC interacts with insulin, nitroglycerin, and activated charcoal, so it should be used under medical supervision in these cases.
Food Sources
Rich sources of cysteine, which is converted to NAC in the body, include chicken, turkey, yogurt, cheese, eggs, sunflower seeds, and legumes.
Time Frame
It is recommended to take NAC before bed to support respiratory health and glutathione production.
Depleted By
NAC can be depleted by factors such as alcohol, antacids, nitrates, anti-emetics, anti-cancer medications, antivirals, antipsychotics, antibiotics, anti-depressants, analgesics, anti-inflammatory medications, NSAIDs, and opioids.