Description
Glycine is a conditionally essential amino acid that the body can synthesize but may require supplementation in cases of injury, illness, or high stress. Glycine plays a key role in the production of glutathione, a potent antioxidant, as well as creatine and collagen, which are essential for muscle health and tissue repair. Its ability to calm the nervous system makes it valuable for promoting better sleep and relaxation. Glycine also acts as a neurotransmitter, potentially benefiting cognitive function and aiding in the treatment of conditions such as schizophrenia and anxiety. Furthermore, glycine has been linked to cancer prevention by reducing blood supply to tumors and supports liver function when used topically to treat leg ulcers. Regular supplementation with glycine offers broad health benefits, from enhancing cognitive performance to promoting tissue regeneration and detoxification.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in glycine can lead to an impaired immune system, muscle loss, diarrhea, slower recovery from illness or injury, mucous membrane ulcers, and cellular damage in the gastrointestinal tract.
Synergy & Antagonism
Glycine works synergistically with serine to promote enhanced sleep time by supporting neurotransmitter function. It also synergizes with magnesium to aid in the production and retention of creatine, which supports muscle recovery and energy production. Glycine may antagonize medications such as clozapine, used for schizophrenia.
Glycine
Warnings
Glycine may interact with clozapine, a drug used to treat schizophrenia. Caution is advised if you are pregnant, breastfeeding, or taking antipsychotic medications.
Food Sources
Rich sources of glycine include nutritional yeast, meat, fish, dairy, legumes, bone broth, eggs, and dried seaweed.
Time Frame
Glycine can be taken anytime, although it is often consumed in the evening for its sleep-enhancing benefits.
Depleted By
Factors that can deplete glycine include antipsychotic medications.