
Description
"Eicosapentaenoic Acid" (EPA) is an omega-3 fatty acid naturally occurring in cold-water fish, known for its polyunsaturated structure. It plays a role in cardiovascular health, supporting circulation and endothelial function. By integrating into cellular membranes, it modulates lipid metabolism and vascular function. EPA also influences neurochemical pathways involved in cognitive balance and mood regulation. Furthermore, it contributes to inflammatory modulation, assisting in physiological adaptation. Essential to omega-3 nutrition, EPA remains vital to metabolic efficiency, brain function, and systemic wellness.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in EPA can lead to decreased growth and intellectual abilities in infants and children, as well as scaly dermatitis, visual problems, and neuropathy.
Synergists & Antagonists
EPA works synergistically with the omega-3 fatty acids DHA and DPA to support brain health, cardiovascular function, and anti-inflammatory processes. No significant antagonistic interactions have been reported.

Eicosapentaenoic Acid
Warnings
EPA interacts with blood thinners, blood pressure medications, diabetes drugs, and aspirin. Excess EPA intake may result in nausea, diarrhea, nosebleeds, and skin rashes.
Food Sources
Rich sources of EPA include mackerel, salmon, oysters, sardines, as well as plant-based sources like flax seeds, chia seeds, hemp seeds, seaweed, and algae.
Time Frame
For optimal absorption, EPA should be taken with meals that contain fat.
Depleted By
EPA levels may be depleted by factors such as alcohol, laxatives, immunosuppressants, hormone replacement therapy, statins, and certain anti-cancer medications.