Description
"Coenzyme Q10" (CoQ10) is a fat-soluble compound naturally found in mitochondria and present in foods like fish, nuts, and organ meats. It plays a central role in ATP synthesis, fueling energy production essential for cellular metabolism. CoQ10 further supports antioxidant defense systems, helping combat oxidative stress and sustain mitochondrial integrity. Through biochemical pathways, it promotes cardiovascular efficiency and metabolic regulation. Critical for cellular resilience, CoQ10 remains fundamental to physiological balance and long-term energy dynamics.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in CoQ10 may lead to heart-related issues such as heart failure, angina, high blood pressure, and mitral valve prolapse. It can also result in muscle weakness and fatigue.
Synergists & Antagonists
CoQ10 interacts synergistically with vitamin E, alpha-lipoic acid, and carnitine to enhance cellular energy production and strengthen antioxidant defense. Since statins contribute to reduced CoQ10 levels, supplementation can help sustain optimal levels.
Coenzyme Q10
Warnings
Caution is advised when using CoQ10 during pregnancy and breastfeeding. It may interact with medications such as Adriamycin (doxorubicin), cholesterol-lowering medications (statins), beta-blockers, and psychotropic drugs. Side effects may include mild insomnia and digestive problems.
Food Sources
Organ Meats, Fatty Fish, Vegetables such as Spinach, Broccoli, Cauliflower, Fruit: Strawberries, Oranges, Legumes, Nuts and Seeds, Eggs, Cereals
Time Frame
CoQ10 is best taken in the afternoon with a meal containing fat to optimize absorption, as it is fat-soluble.
Depleted By
CoQ10 levels can be depleted by various factors, including antacids, nicotine, anti-emetics, hormone replacements, diuretics, antidiabetic medications, statins, anti-cancer drugs, blood thinners, blood pressure medications, cardiac regulators, antivirals, antipsychotics, antihistamines, antibiotics, antidepressants, as well as aging, poor diet, stress, and infections.