
Description
"Ashwagandha" (Withania somnifera) is a perennial shrub native to India, the Middle East, and parts of Africa, traditionally cultivated for its roots and leaves. It contains withanolides, alkaloids, and flavonoids, which interact with neurotransmitter pathways, cortisol metabolism, and enzymatic processes. Additionally, its phytochemical composition influences adaptive responses linked to neuroendocrine and cellular signaling networks. As a bioactive botanical, ashwagandha remains a key component in traditional herbal systems and plant-based formulations.
Functions in the Body
Category
Deficiency Symptoms
As ashwagandha is not an essential nutrient, there are no deficiency symptoms associated with its absence.
Synergists & Antagonists
Ashwagandha is commonly used with rhodiola, ginseng, and holy basil to support stress management and balance adrenal function. No known antagonistic effects have been reported.

Ashwagandha
Warnings
Ashwagandha should be avoided during pregnancy and breastfeeding due to limited research on its safety. It is also not recommended for individuals with autoimmune diseases or hyperthyroidism without consulting a healthcare provider.
Food Sources
Ashwagandha is typically consumed as a supplement or herbal extract, as it is not a common dietary food source.
Time Frame
Ashwagandha is best taken with meals that contain fat, as this enhances its absorption and effectiveness.
Depleted By
Ashwagandha is not depleted by specific dietary or lifestyle factors.