Description
“Arginine” is a semi-essential amino acid naturally present in protein-rich foods like meat, dairy, and legumes. It serves as a precursor to nitric oxide (NO), a signaling molecule that influences vascular tone, circulation, and metabolic regulation. In addition, arginine is involved in protein synthesis, immune function, and cellular repair. While the body produces this amino acid, dietary intake helps sustain adequate levels. Its role in physiological processes makes arginine an important component of metabolic and cardiovascular function.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in arginine can lead to symptoms such as stiffness in the legs, slower growth, hair loss, skin rash, delayed development, intellectual disability, slow wound healing, and constipation.
Synergists & Antagonists
Arginine is commonly paired with citrulline, ornithine, and nitric oxide boosters to promote blood flow. However, it may antagonize lysine due to metabolic competition, and high glutamine intake could further reduce its effectiveness.
Arginine
Warnings
Overdosing on arginine may cause abdominal pain, bloating, diarrhea, and exacerbate conditions like gout. In people with asthma, it may cause breathing problems. It can also interact with medications for high blood pressure, erectile dysfunction, and heart conditions, so caution is advised.
Food Sources
Rich sources of arginine include nutritional yeast, nuts, seeds, meat, legumes, seaweed, lentils, oats, corn, and chocolate.
Time Frame
Arginine can be taken at any time of day, with no specific timing required for its benefits.
Depleted By
Arginine levels can be depleted by a poor diet and excessive intake of lysine, which competes with arginine for absorption.