Description
"Acetyl L-Carnitine" (ALC) is a naturally occurring compound derived from L-carnitine, essential for brain function and energy production. It plays a key role in transporting fatty acids into mitochondria, where they are converted into energy, supporting mental clarity and physical endurance. While the body produces L-carnitine, dietary sources like meat and dairy contribute to overall levels. ALC’s involvement in neurotransmitter activity may influence focus, memory, and cognitive health. Nutrients like vitamin C and iron help maintain carnitine metabolism.
Functions in the Body
Category
Deficiency Symptoms
While rare, deficiency in acetyl-L-carnitine may occur in certain populations, such as premature infants or individuals with genetic conditions affecting the metabolism of long-chain fatty acids. Symptoms may include muscle weakness and low energy levels.
Synergists & Antagonists
Acetyl-L-carnitine is commonly paired with CoQ10, alpha-lipoic acid, omega-3 fatty acids, and other carnitine forms (L-carnitine, propionyl-L-carnitine) to support mitochondrial energy production. However, it acts as an antagonist when taken alongside thyroid medications, as it may interfere with thyroid hormone activity.
Acetyl-L-Carnitine
Warnings
Certain antibiotics containing pivalic acid, such as pivampicillin and pivmecillinam, can deplete carnitine levels when metabolized. This is especially relevant for individuals on valproic acid (an anticonvulsant), as both medications can disrupt carnitine metabolism. Monitoring carnitine levels and considering supplementation may be necessary, especially in long-term use.
Food Sources
Rich sources of acetyl-L-carnitine include beef, pork, milk, cod, chicken, avocado, and asparagus.
Time Frame
For best results, acetyl-L-carnitine is often taken in the morning, as it can support energy metabolism throughout the day.
Depleted By
There are no well-documented factors that significantly deplete acetyl-L-carnitine in the body.