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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Hemoglobin A1C

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HBA1C

Description

Hemoglobin A1C test, sometimes called the eAG test, checks the sugar attached to the hemoglobin in your blood. Unlike a one-time blood sugar check, it provides an overview of your average levels over the past two to three months. It’s a key test for diagnosing diabetes or prediabetes and seeing how well blood sugar levels are under control. For the test, your doctor takes a small blood sample to analyze. High A1C levels might mean your blood sugar isn’t under control, which can raise the chances of heart disease or nerve damage. Healthy A1C levels show your blood sugar is where it should be. This test is especially helpful for those managing diabetes or experiencing symptoms like fatigue or frequent urination. The results show your doctor what’s working and if adjustments to your diet, medications, or activity could improve how you feel. Regular A1C tests are key to managing diabetes and reducing the risk of complications.

Hemoglobin A1C test, sometimes called the eAG test, checks the sugar attached to the hemoglobin in your blood. Unlike a one-time blood sugar check, it provides an overview of your average levels over the past two to three months. It’s a key test for diagnosing diabetes or prediabetes and seeing how well blood sugar levels are under control. For the test, your doctor takes a small blood sample to analyze. High A1C levels might mean your blood sugar isn’t under control, which can raise the chances of heart disease or nerve damage. Healthy A1C levels show your blood sugar is where it should be. This test is especially helpful for those managing diabetes or experiencing symptoms like fatigue or frequent urination. The results show your doctor what’s working and if adjustments to your diet, medications, or activity could improve how you feel. Regular A1C tests are key to managing diabetes and reducing the risk of complications.

Procedure

Invasive

Sample Type

Blood – Whole Blood

Test Category

Glycoproteins, Proteins

Procedure Category

Blood Draw

Units

Percentage | Milligrams Per Deciliter

Test Groups

Basic Blood Sugar Group: This group encompasses fundamental tests related to blood sugar, offering essential insights into glycemic control and metabolic health. Complete Blood Sugar Group: This expanded group includes a more comprehensive set of tests, offering a thorough evaluation of diverse facets of blood sugar levels for a more detailed understanding of metabolic health. Basic Cardiovascular Group: This group includes fundamental tests targeting essential markers related to cardiovascular health, providing foundational insights into cholesterol levels, blood pressure, and other key factors. Basic Inflammation Group: This set of tests helps evaluate the body's inflammatory response, providing valuable information for diagnosing and managing inflammatory conditions. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Complete Inflammation Group: Extensive tests offer a comprehensive assessment of inflammatory markers, yielding detailed insights into inflammation levels and related health conditions.

Optimal Range

For All Individuals:

  • Conventional Unit: HbA1c: 4.5–5.4% | eAG: 82–108 mg/dL

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: HbA1c: <5.7% | eAG: 70–126 mg/dL

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Chronic kidney disease

  • Chronic liver disease

  • Gestational diabetes (Diabetes during pregnancy)

  • Hemoglobinopathies (such as sickle cell disease or thalassemia)

  • Prediabetes (Early stage of diabetes)

  • Type 1 diabetes (Autoimmune destruction of insulin-producing cells)

  • Type 2 diabetes (Insulin resistance or inadequate insulin production)

Key Reasons For Testing

  • Diabetes Diagnosis: Detects diabetes by reflecting average blood glucose levels over the past 2–3 months.

  • Long-term Glycemic Control: Evaluates glycemic trends, aiding in diabetes management and treatment planning.

  • Treatment Monitoring: Tracks the effectiveness of lifestyle and medication interventions.

  • Complication Risk Assessment: Identifies risks for cardiovascular, renal, and neuropathic complications.

  • Treatment Adjustment: Guides dosage changes for medications or insulin.

  • High-risk Screening: Screens individuals with prediabetes or a family history of diabetes to enable early intervention.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Lee SW, Kim HC, Lee YH, et al. Association between HbA1c and carotid atherosclerosis among elderly Koreans with normal fasting glucose. PLoS One. 2017;12(2):e0171766.
[2] Ribeiro RT, Macedo MP, Raposo JF. HbA1c, Fructosamine, and Glycated Albumin in the Detection of Dysglycaemic Conditions. Curr Diabetes Rev. 2016;12(1):14-19.
[3] Little RR, Sacks DB. The National Glycohemoglobin Standardization Program: A five-year progress report. Clin Chem. 1999;45(12):2075-2079.
[4] Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ; A1c-Derived Average Glucose Study Group. Translating the A1C assay into estimated average glucose values. Diabetes Care. 2008;31(8):1473-1478.
[5] Sacks DB, Arnold M, Bakris GL, et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem. 2011;57(6):e1-e47.
[6] World Health Organization. Use of Glycated Haemoglobin (HbA1c) in the Diagnosis of Diabetes Mellitus: Abbreviated Report of a WHO Consultation. Geneva, Switzerland: WHO Press; 2011.
[7] Weykamp C, John WG, Mosca A. A review of the challenge in measuring hemoglobin A1c. J Diabetes Sci Technol.2009;3(3):439-445.
[8] Edelman SV, Olsen MK, Dudley TK, Harris AC. Utility of HbA1c in predicting diabetes risk. Diabetes Care.2004;27(10):2485-2489.
[9] Hanas R, John G; International HbA1c Consensus Committee. 2010 Consensus Statement on the worldwide standardization of the hemoglobin A1c measurement. Diabetes Care. 2010;33(8):1903-1904.
[10] Selvin E, Steffes MW, Zhu H, et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med. 2010;362(9):800-811.
[11] van der Heijden AA, Rauh SP, Dekker JM, et al. The predictive value of HbA1c for type 2 diabetes and cardiovascular disease in the general population: a systematic review. Diabetologia. 2012;55(4):885-897.
[12] Bonora E, Tuomilehto J. The pros and cons of diagnosing diabetes with HbA1c. Diabetologia. 2011;54(5):695-699.
[13] Bloomgarden ZT. A1c: recommendations, debates, and questions. Clin Ther. 2010;32(5):767-781.
[14] Davidson MB, Schriger DL, Peters AL, Lorber B. Revisiting the role of HbA1c in the diagnosis of diabetes. Diabetes Care. 2014;37(8):e136-e137.

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