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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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CATECHOLAMINE BLOOD

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CAB

Description

Catecholamine Blood test looks for hormones in your blood, including adrenaline, noradrenaline, and dopamine. These hormones are made by your adrenal glands and released when your body reacts to stress. Doctors may order this test to help find conditions like pheochromocytoma, neuroblastoma, or other rare tumors linked to the adrenal glands or nervous system. A blood sample is usually taken during or shortly after symptoms like high blood pressure, a fast heartbeat, or severe headaches. High levels of these hormones might point to an overactive adrenal gland or a stress-related disorder. This test is particularly useful for people experiencing unexplained hypertension, palpitations, or excessive sweating. The results help doctors find out what’s causing your symptoms and recommend treatments, like medications, surgery, or lifestyle adjustments. Regular testing can also track progress and support long-term care for conditions related to abnormal catecholamine levels.

Catecholamine Blood test looks for hormones in your blood, including adrenaline, noradrenaline, and dopamine. These hormones are made by your adrenal glands and released when your body reacts to stress. Doctors may order this test to help find conditions like pheochromocytoma, neuroblastoma, or other rare tumors linked to the adrenal glands or nervous system. A blood sample is usually taken during or shortly after symptoms like high blood pressure, a fast heartbeat, or severe headaches. High levels of these hormones might point to an overactive adrenal gland or a stress-related disorder. This test is particularly useful for people experiencing unexplained hypertension, palpitations, or excessive sweating. The results help doctors find out what’s causing your symptoms and recommend treatments, like medications, surgery, or lifestyle adjustments. Regular testing can also track progress and support long-term care for conditions related to abnormal catecholamine levels.

Procedure

Invasive

Sample Type

Blood – Plasma

Test Category

Hormones

Procedure Category

Blood Draw

Units

Picograms Per Milliliter

Test Groups

Hormone Health Group: Its focus is on evaluating hormone levels and function, providing insights into hormonal balance and associated health conditions.

Optimal Range

For All Individuals:

  • Conventional Unit: Epinephrine: < 100.00 pg/mL | Norepinephrine: 200.00–600.00 pg/mL | Dopamine: 10.00–20.00 pg/mL

  • SI Unit: Not Frequently Used

Normal Range

For All Individuals:

  • Conventional Unit: Epinephrine: 0.00–140.00 pg/mL | Norepinephrine: 70.00–750.00 pg/mL | Dopamine: 0.00–30.00 pg/mL

  • SI Unit: Not Frequently Used

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Ganglioblastoma (a rare type of brain tumor that originates from neural crest cells)

  • Ganglioneuroma (a benign tumor derived from neural crest cells found in the sympathetic nervous system)

  • Neuroblastoma (a type of cancer that forms in nerve tissue)

  • Pheochromocytoma (a rare tumor of the adrenal glands that produces excess adrenaline and noradrenaline)

  • Severe stress

Key Reasons For Testing

  • Diagnosis of Pheochromocytoma: Identifies rare adrenal tumors causing high blood pressure and symptoms due to excess catecholamines.

  • Assessment of Hypertensive Crisis: Detects severe blood pressure spikes caused by hormone surges.

  • Evaluation of Orthostatic Hypotension: Investigates blood pressure drops caused by inadequate hormone release when standing.

  • Diagnosis of Neuroendocrine Tumors: Helps detect tumors such as paragangliomas or neuroblastomas.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Goldstein DS, Eisenhofer G, Kopin IJ. Sources and significance of plasma levels of catechols and their metabolites in humans. J Pharmacol Exp Ther. 2003;305(3):800-811.
[2] Peaston RT, Weinkove C. Measurement of catecholamines and their metabolites. Ann Clin Biochem. 2004;41(Pt 1):17-38.
[3] Lenders JW, Eisenhofer G, Mannelli M, Pacak K. Phaeochromocytoma. Lancet. 2005;366(9486):665-675.
[4] Kudielka BM, Hellhammer DH, Wüst S. Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology. 2009;34(1):2-18.
[5] Eisenhofer G, Goldstein DS, Walther MM, et al. Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results. J Clin Endocrinol Metab. 2003;88(6):2656-2666.
[6] Goldstein DS, Stull R, Eisenhofer G, Gill JR, Sisson JC, Holmes C. Plasma catecholamines and their responses during cholinergic blockade in humans. Am J Physiol. 1987;252(1 Pt 2).
[7] Grossman E, Irony I, Dovrish Z, et al. Increased urinary dopamine output in patients with pheochromocytoma. J Clin Endocrinol Metab. 1992;75(3):810-813.
[8] Kline GA, Prebtani AP. Primary hypertension and catecholamines. Clin Endocrinol (Oxf). 2007;66(5):591-598.
[9] Thosar SS, Perdomo SJ, Mather KJ, et al. Effects of sedentary behavior on insulin sensitivity and plasma catecholamines. Metabolism. 2019;94:23-29.
[10] Bornstein SR, Breidert M, Ehrhart-Bornstein M, Scherbaum WA. Plasma catecholamines in neuroendocrine tumors. Horm Metab Res. 1996;28(8):378-384.
[11] Travin MI, Cohn PF. Plasma catecholamines and their application to clinical practice. Am Heart J. 1983;105(3):528-535.
[12] Manger WM, Gifford RW Jr. Clinical and experimental pheochromocytoma. Endocr Rev. 1985;6(3):362-388.
[13] Pussard E, Guigueno N, Giboudeau J. Variability of plasma catecholamines in humans. Clin Chem Lab Med.2007;45(2):257-262.

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